How do enhancers and silencers influence transcription in eukaryotes?

How do enhancers and silencers influence transcription in eukaryotes?

• A. Enhancers directly bind RNA polymerase to start transcription.
• B. Enhancers increase transcription by looping to promoters and recruiting activators; silencers recruit repressors and modify chromatin to reduce transcription.
• C. Both enhancers and silencers are located only in promoters and do not affect transcription.
• D. Silencers promote transcription by opening chromatin.

Answer: (B)