How do transcription factors influence promoter activity and gene expression integration with signaling pathways?

How do transcription factors influence promoter activity and gene expression integration with signaling pathways?

• A. They degrade signaling molecules to prevent transcription.
• B. They recruit coactivators or corepressors and bind DNA motifs to modulate transcription initiation, integrating signals from pathways.
• C. They synthesize transcription factors themselves to regulate promoter activity.
• D. They modify chromatin structure by directly methylating DNA at promoter sites.

Answer: (B)