What are the major DNA repair pathways and the types of damage they fix?

What are the major DNA repair pathways and the types of damage they fix?

• A. Translesion synthesis repairs all lesions by polymerase switching.
• B. Base excision repair for small base lesions; nucleotide excision repair for bulky distortions; mismatch repair for replication errors; homologous recombination and non-homologous end joining for double-strand breaks.
• C. Only base excision repair exists.
• D. Mismatch repair fixes bulky distortions.

Answer: (B)